WebApr 6, 2024 · Dronedarone and sotalol are not recommended in AF guidelines, 3, 4 and are contraindicated in AF patients with New York Heart Association (NYHA) class IV heart failure or severe LVEF dysfunction (in the absence of an implantable cardioverter defibrillator with sotalol). 44, 45 However, physicians may consider dronedarone or … WebBackground: There are limited comparative data on safety and efficacy within commonly used Vaughan-Williams (VW) class III antiarrhythmic drugs (AADs) for maintenance of sinus rhythm in adults with atrial fibrillation (AF). Hypothesis: We hypothesized that dronedarone and sotalol, two commonly prescribed VW class III AADs with class II properties, have …
Modernized Classification of Cardiac Antiarrhythmic …
WebSotalol. Sotalol, a newer agent available in the United States, is a class III antiarrhythmic that also has nonselective β-adrenergic blocking effects. The β-blocker effects predominate at small doses, whereas the class III effects are realized at larger doses. Sotalol is indicated for a number of tachydysrhythmias that are difficult to control. Sotalol is a non-selective beta-adrenergic receptor blocker which has both class II and class III antiarrhythmic properties. Sotalol was first described in 1964 and came into medical use in 1974. It is available as a generic medication. See more Sotalol, sold under the brand name Betapace among others, is a medication used to treat and prevent abnormal heart rhythms. It is only recommended in those with significant abnormal heart rhythms due to potentially … See more According to the U.S. Food and Drug Administration (FDA), sotalol can be validly used to maintain a normal heart rhythm in people with life-threatening ventricular arrhythmias (e.g., ventricular tachycardia), or very symptomatic atrial fibrillation or flutter. … See more Over 10% of oral sotalol users experience fatigue, dizziness, lightheadedness, headache, weakness, nausea, shortness of breath, bradycardia (slow heart rate), a sensation of the heart beating too hard, fast, or irregularly, or chest pain. Higher doses of sotalol … See more Trade names for Sotalol include Betapace and Betapace AF (Berlex Laboratories), Sotalex and Sotacor (Bristol-Myers Squibb), and Sotylize (Arbor Pharmaceuticals). See more According to the FDA, sotalol should not be used in people with a waking heart rate lower than 50 beats per minute. It should not be used in people with sick sinus syndrome, long QT syndrome, cardiogenic shock, uncontrolled heart failure, asthma or a related … See more Beta-blocker action Sotalol non-selectively binds to both β1- and β2-adrenergic receptors preventing activation of the receptors by their stimulatory ligand ( See more Sotalol was first synthesized in 1960 by A. A. Larsen of Mead-Johnson Pharmaceutical. It was originally recognized for its blood pressure lowering effects and its … See more biscayne heights grand island fl
Sotalol Side Effects: Common, Severe, Long Term - Drugs.com
WebThe concomitant use of other beta-blocking agents with sotalol may result in additive Class II effects. Other drugs prolonging the QT-interval . Sotalol 40mg Tablets should be given with extreme caution in conjunction with other drugs known to prolong the QT-interval such as phenothiazines, tricyclic antidepressants, terfenadine and astemizole. Websotalol (Rx) Brand and Other Names: Betapace, Betapace AF, more... Classes: Antidysrhythmics, II; Antidysrhythmics, III; Beta-Blockers, Nonselective Print Dosing & Uses AdultPediatric Dosage... dark brown and clumpy period blood